Pierre TUFFERY
Modélisation computationnelle des interactions Protéines-ligands
Unité de recherche: UMR8251 – EURL_1133
Université Paris Cité
Université Paris Cité
Unité de Biologie Fonctionnelle et Adaptative (BFA)
35 rue Hélène Brion
Case 7113
75205 Paris Cedex 13
Spécialité : Approches in silico, Bioinformatique structurale, Modélisation moléculaire
Directeur de l’unité de rattachement : Christophe MAGNAN
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Responsable de l’équipe de recherche
TUFFERY Pierre
Courriel : pierre.tuffery@u-paris.fr
Tél : 01 57 27 83 74
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Composition de l’équipe de recherche
- BRUZZONI-GIOVAVNELLI Heriberto (MCU-PH, HDR)
- CHEVROLLIER Nicolas (IR)
- DONG Chang-Zhi (PR, HDR)
- MOROY Gautier (MC, HDR)
- MURAIL Samuel (MCn HDR)
- REY Julien (IR)
- ROUSSEL Pascal (CR, HDR)
- SIRRI-ROUSSEL Valentina (CR°
- STRATMANN Dirk (MC)
- TUFFERY Pierre (DR, HDR)
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5 publications récentes de l’équipe de recherche
Stratmann D, Moroy G, Tuffery P, Murail S. (2025) Simulated Solute Tempering 2: An Efficient and Practical Approach to Protein Conformational Sampling and Binding Events. Journal of Chemical Theory and Computation.21(21):10705-18.
Dominguez-Meijide J, Murail S, Boudjelloul R, Rebollo A, Tuffery P. (2025) Exploring the interaction between a LRRK2/PP1CA interfering peptide and PP1CA. Journal of Molecular Graphics and Modelling. 141:109140.
Karami, Y., Murail, S., Giribaldi, J., Lefranc, B., Defontaine, F., Lesouhaitier, O., Leprince, J., de Vries, S. & Tufféry, P. (2023). Exploring a Structural Data Mining Approach to Design Linkers for Head-to-Tail Peptide Cyclization. Journal of Chemical Information and Modeling, 63(20):6436-6450.
Rey, J., Murail, S., de Vries, S., Derreumaux, P. & Tufféry, P. (2023). PEP-FOLD4: a pH-dependent force field for peptide structure prediction in aqueous solution. Nucleic Acids Research, 51(W1):W432-W437
Ghoula, M., Deyawe Kongmeneck, A., Eid, R., Camproux, A.C. & Moroy G. (2023). Comparative Study of the Mutations Observed in the SARS-CoV-2 RBD Variants of Concern and Their Impact on the Interaction with the ACE2 Protein. Journal of Physical Chemistry B, 127(40):8586-8602.