Unité de recherche : UMR8002
Université Paris Cité
Faculté des Sciences Fondamentales et Biomédicales
Integrative Neuroscience and Cognition Center (INCC)
45 rue des Saints-Pères
75270 Paris cedex 06
Spécialité : Neurosciences
Directeur de l’unité de rattachement : Florian WASZAK
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Responsable de l’équipe de recherche
GIROS Bruno
Courriel : bruno.giros@mcgill.ca
Tel: 01 76 53 24 66
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Composition de l’équipe de recherche
- De GOIS Stéphanie (IR)
- GIROS Bruno (DR, HDR)
- ISINGRINI lsa (CR)
- MARZO Aude (MCU)
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5 publications récentes de l’équipe de recherche
Role of the locus coeruleus-noradrenergic system in stress-related psychopathology and resilience: Clinical and pre-clinical evidences. Slavova D, Ortiz V, Blaise M, Bairachnaya M, Giros B, Isingrini E. Neurosci Biobehav Rev. 2024 Oct 18;167:105925. doi: 10.1016/j.neubiorev.2024.105925.
Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs. Bonnavion P, Varin C, Fakhfouri G, Martinez Olondo P, De Groote A, Cornil A, Lorenzo Lopez R, Pozuelo Fernandez E, Isingrini E, Rainer Q, Xu K, Tzavara E, Vigneault E, Dumas S, de Kerchove d’Exaerde A, Giros B. Nat Neurosci. 2024 Sep;27(9):1783-1793. doi: 10.1038/s41593-024-01694-4.
Rocchetti J, Fasano C, Dal-Bo G, Guma E, El Mestikawy S, Wong TP, Fakhfouri G, Giros B. Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride. PLoS One. 2023 Aug 25;18(8):e0289770.
Isingrini E, Guinaudie C, Perret L, Guma E, Gorgievski V, Blum ID, Colby-Milley J, Bairachnaya M, Mella S, Adamantidis A, Storch KF, Giros B. Behavioral and Transcriptomic Changes Following Brain-Specific Loss of Noradrenergic Transmission. Biomolecules. 2023 Mar 10;13(3):511.
Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F, Mechawar N, Williams S, Gratton A, Giros B. Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons. Nat Neurosci. 2016 Apr;19(4):560-3.