< Retour à la liste
profil pic GIROSBruno

Bruno GIROS

Pathophysiologie des Maladies Psychiatriques

bruno.giros@u-paris.fr

Unité de recherche : UMR8002
Université Paris Cité

Faculté des Sciences Fondamentales et Biomédicales
Integrative Neuroscience and Cognition Center (INCC)
45 rue des Saints-Pères
75270 Paris cedex 06

Spécialité Neurosciences

Directeur de l’unité de rattachement : Florian WASZAK

__________________________________________________________________________________________________________________

Responsable de l’équipe de recherche

GIROS Bruno
Courriel : bruno.giros@u-paris.fr
Tel: G01 76 53 24 66

_________________________________________________________________________________________________

Composition de l’équipe de recherche

  • De GOIS Stéphanie (IR)
  • GIROS Bruno (DR, HDR)
  • ISINGRINI lsa (CR)

__________________________________________________________________________________________________________________

5 publications récentes de l’équipe de recherche

Rocchetti J, Fasano C, Dal-Bo G, Guma E, El Mestikawy S, Wong TP, Fakhfouri G, Giros B. Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride. PLoS One. 2023 Aug 25;18(8):e0289770.

Isingrini E, Guinaudie C, Perret L, Guma E, Gorgievski V, Blum ID, Colby-Milley J, Bairachnaya M, Mella S, Adamantidis A, Storch KF, Giros B. Behavioral and Transcriptomic Changes Following Brain-Specific Loss of Noradrenergic Transmission. Biomolecules. 2023 Mar 10;13(3):511.

Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu AP, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM, Giros B. Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration. Sci Rep. 2019 May 24;9(1):7850.

Isingrini E, Guinaudie C, C Perret L, Rainer Q, Moquin L, Gratton A, Giros B. Genetic elimination of dopamine vesicular stocks in the nigrostriatal pathway replicates Parkinson’s disease motor symptoms without neuronal degeneration in adult mice. Sci Rep. 2017 Sep 29;7(1):12432.

Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F, Mechawar N, Williams S, Gratton A, Giros B. Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons. Nat Neurosci. 2016 Apr;19(4):560-3.