Unité de recherche : UMR_S1140
Université Paris Cité
Faculté des Sciences Pharmaceutiques et Biologiques
Innovations Thérapeutiques en Hémostase
4 av. de l’Observatoire
75270 Paris Cedex 06
Spécialité : Biochimie , Biologie cellulaire , Biothérapies , Hémostase , Médicament , Pharmacologie , Recherche clinique
Directrice de l’unité de rattachement : GAUSSEM Pascale
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Responsable de l’équipe de recherche
GAUSSEM Pascale
Courriel : pascale.gaussem@u-paris.fr
01 53 73 99 39
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Composition de l’équipe de recherche
- ALSAC Jean-Marc (PU-PH, HDR)
- BACHELOT-LOZA Christilla (CR, HDR)
- CHOLLEY Bernard (PU-PH, HDR)
- DOMINGUES Alison (MC)
- EL BATTI Salm (PU-PH, HDR)
- GANDRILLE Sophie (DR, HDR)
- GAUSSEM Pascale (PU-PH, HDR)
- GENDRON Nicolas (PH)
- GODIER Anne (PH, HDR)
- GUERIN Coralie (PH)
- JOURDI Georges (MCU-PH)
- MARGAILL Isabelle (PR, HDR)
- NIVET-ANTOINE Valérie (PU-PH, HDR)
- PAUTAS Éric (PU-PH, HDR)
- PLANQUETTE Benjamin (PU-PH, HDR)
- ROSSI Elisa (MC, HDR)
- SIGURET Virginie (PU-PH, HDR)
- SMADJA David (PU-PH, HDR)
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5 publications récentes et significatives de l’équipe de recherche
Foulon-Pinto G, Lafuente-Lafuente C, Jourdi G, Le Guen J, Tall F, Puymirat E, Delrue M, RIVIERE l, ketz f, Gouin-Thibault I, mullier f, GausseM P, Pautas P, Lecompte t, Curis e, Siguret v. Assessment of Direct oral Anticoagulants in GEriatrics (Adage) study: rivaroxaban/apixaban concentrations and thrombin generation profiles in NVAF very elderly patients. Thromb Haemostas. 2023, in press (IF: 5.24)
Philippe A, Günther S, Rancic J, Cavagna P, Renaud B, Gendron N, Mousseaux E, Hua-Huy T, Reverdito G, Planquette B, Sanchez O, Gaussem P, Salmon D, Diehl JL, Smadja DM. VEGF-A plasma levels are associated with impaired DLCO and radiological sequelae in long COVID patients. Angiogenesis. 2023 ; In press
Philippe A, Chocron R, Gendron N, Bory O, Beauvais A, Peron N, Khider L, Guerin CL, Goudot G, Levasseur F, Peronino C, Duchemin J, Brichet J, Sourdeau E, Desvard F, Bertil S, Pene F, Cheurfa C, Szwebel TA, Planquette B, Rivet N, Jourdi G, Hauw-Berlemont C, Hermann B, Gaussem P, Mirault T, Terrier B, Sanchez O, Diehl JL, Fontenay M, Smadja DM. Circulating Von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality. Angiogenesis, 2021: 505-517 (IF 9,59)
Smadja DM, Rossi E, Haviari S, Bieche I, Cras A, Gaussem P. Thrombin receptor PAR1 silencing in endothelial colony-forming cells modifies stemness and vasculogenic properties. J Thromb Haemost. 2023 ; 21:3640-3648
Rossi E, Pericacho M, Kauskot A, Gamella-Pozuelo L, Reboul E, Leuci A, Egido-Turrion C, El Hamaoui D, Marchelli A, Fernández FJ, Margaill I, Vega MC, Gaussem P, Pasquali S, Smadja DM, Bachelot-Loza C, Bernabeu C. Soluble endoglin reduces thrombus formation and platelet aggregation via interaction with αIIbβ3 integrin. J Thromb Haemost. 2023 ; 21:1943-1956 Stem Cell Rev. 2019 ; 15 : 590-600
Nascimbene A, Bark D, Smadja DM. Hemocompatibility and Biophysical Interface of Left Ventricular Assist Devices and Total Artificial Hearts. Blood 2023 Oct 27:blood.2023018096. doi: 10.1182/blood.2022018096.
BELLEVILLE-ROLLAND T, LEUCI A, MANSOUR A, DECOUTURE B, MARTIN F, CHASSAC S, ROUAUD M, GUERINEAU H, DIZIER B, PIDARD D, GAUSSEM P, BACHELOT-LOZA C. Membrane lipid rafts do not play a major role in MRP4-dependent regulation of cAMP pathway in platelets. Thromb Haemost 2021, 121:1628–1636.