Anne-Marie WEHENKEL
Unité des mécanismes du cycle cellulaire bactérien
Unité de Recherche : Unité des mécanismes du cycle cellulaire bactérien
Institut Pasteur
25-28 rue du Dr. Roux
75015 Paris
Spécialité : Biochimie, Biologie moléculaire, Biologie structurale, Imageries, Interface chimie-biologie, Médicament, Microbiologie
Directeur de l’unité de rattachement : Anne-Marie WENHEKEL
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Responsable de l’équipe de recherche
WEHENKEL Anne-Marie
Courriel : anne-marie.wehenkel@pasteur.fr
Tél. : 01 76 53 52 33
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Composition de l’équipe de recherche :
- BEN ASSAYA Mathilde (IR)
- BELLINZONI Marco (CR, HDR)
- MARTINEZ Mariano (IR)
- PETRELLA Stéphanie (MC, HDR)
- WEHENKEL Anne-Marie (CL, HDR)
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5 publications récentes de l’équipe
Gedeon#*, A., Yab#, E., Dinut, A., Sadowski, E., Capton, E., Dreneau, A., Petit, J., Gioia, B., Piveteau, C., Djaout, K., Lecat, E., Wehenkel, A., Gubellini, F., Mechaly, A., Alzari, P., Deprez, B., Baulard, A., Aubry, A., Willand*, N. & Petrella#, S. Rational design and molecular mechanism of inhibition of a first-in-class triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase. 2024 iScience Vol 27, 110967.# Corresponding author
Martinez*, M., Petit*, J., Leyva*, A., Sogues, A., Megrian, D., Rodriguez, A., Gaday, Q., Ben Assaya, M., Portela, M., Haouz, A., Ducret, A., Grangeasse, C., Alzari, P. M., Durán#, R., Wehenkel#, A. Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation. 2023 Nat Microbiol 8, 1896–1910. *equal contribution # Corresponding author PMID: 37679597
Yang L, Wagner T, Mechaly A, Boyko A, Bruch EM, Megrian D, Gubellini F, Alzari PM, Bellinzoni# M. High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase. Nat Commun. 2023 10;14:4851. doi: 10.1038/s41467-023-40253-6. PMID: 37563123; # Corresponding author
Gaday, Q., Megrian, D., Carloni, G., Martinez, M., Sokolova, B., Ben Assaya, M., Legrand, P., Brûlé, S., Haouz, A., Wehenkel#, A., Alzari#, P.M. Structural basis of FtsEX-independent RipA-mediated cell separation in Corynebacteriales. 2022 Proc Natl Assoc Sci USA, 119, e2214599119. # Corresponding author PMID: 36469781
Sogues, A., Martinez, M., Gaday, Q., Ben-Assaya, M., Graña, M., Voegele, A., VanNieuwenhze, M., England, P., Haouz, A., Chenal, A., Trepout, S., Duran, R., Wehenkel, A. # & Alzari, PM.# 2020 Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum. Nat Commun 11, 1641. # Corresponding author. PMID: 32242019