Unité de Recherche : Unité G5 + Biologie Structurale des Maladies Infectieuses
Institut Pasteur
28 Rue du Docteur Roux
75015 PARIS
Spécialité : Biologie structurale,
Directeur de l’unité de rattachement : Pablo GUARDADO-CALVO
Responsable de l’équipe de recherche :
Pablo GUARDADO-CALVO
Courriel : pablo.guardado-calvo@pasteur.fr
Tel : 01 40 61 32 53
Composition de l’équipe de recherche
- GUARDADO-CALVO Pablo (CR-HDR)
- MEOLA Annalisa (IR)
5 publications récentes de l’équipe de recherche
Mittler E, Serris A, Esterman ES, Florez C, Polanco LC, O’Brien CM, Sloug MM, Tynell J, Gröning R, Sun Y, Abelson DM, Wec AZ, Haslwanter D, Keller M, Ye C, Bakken RR, Jangra RK, Dye JM, Ahlm C, Rappazzo CG, Ulrich RG, Zeitlin L, Geoghegan JC, Bradfute SB, Sidoli S, Forsell MNE, Strandin T, Rey FA, Herbert AS, Walker LM, Chandran K, Guardado-Calvo P. Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody. Sci Transl Med 2023 PMID:37315110.
Serris A, Stass R, Bignon EA, Muena NA, Manuguerra JC, Jangra RK, Li S, Chandran K, Tischler ND, Huiskonen JT, Rey FA, Guardado-Calvo P. The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell 2020 PMID:32937107
Guardado-Calvo P, Atkovska K, Jeffers SA, Grau N, Backovic M, Pérez-Vargas J, de Boer SM, Tortorici MA, Pehau-Arnaudet G, Lepault J, England P, Rottier PJ, Bosch BJ, Hub JS, Rey FA. A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion. Science 2017 PMID: 29097548.
Guardado-Calvo P, Bignon EA, Stettner E, Jeffers SA, Pérez-Vargas J, Pehau-Arnaudet G, Tortorici MA, Jestin JL, England P, Tischler ND, Rey FA. Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc. PLoS Pathog 2016 PMID: 27783711
Vernuccio R, Guardado-Calvo P. Neutralization Determinants on Poxviruses. Viruses 2023 PMID: 38140637