LAURENT-PUIG Pierre

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Unité de recherche : UMR_S1138
Université Paris Cité

Centre de Recherche des Cordeliers
15 rue de l’École de Médecine
75006 Paris

Spécialité : Biologie cellulaire, Biologie moléculaire, Interface chimie-biologie, Pharmacologie, Recherche clinique, Toxicologie

Directrice de l’unité de rattachement : Jessica ZUCMAN-ROSSI

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Responsable de l’équipe de recherche

LAURENT-PUIG Pierre
Courriel : pierre.laurent-puig@u-paris.fr
Tel: 01 44 27 91 58

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Composition de l’équipe de recherche

• ALEXANDRE Jérôme (PU-PH, HDR)
• AUDENET François (MCU-PH, HDR)
• AZAIS Henri (PH, HDR)
• BACHET Jean-Baptiste (PU-PH, HDR)
• BATS Anne-Sophie (PU-PH, HDR)
• BENAIM Léonor (PH, HDR)
• BEAUNE Philippe (PREM, HDR)
• BEISNE Guillaume (PH)
• BLONS HELENE (PU-PH, HDR)
• BOIGE Valérie (PH)
• BORGHESE Bruno (PU-PH,HDR)
• CHABA Kariman (IR)
• DJOUADI Fatima (DR, HDR)
• GALLOIS Claire (MCU-PH)
• GARINET Simon (PHU)
• GAUDET Antoine (PHU)
• KAROUI Mehdi (PU-PH, HDR)
• LAURENT-PUIG Pierre (PU-PH, HDR)
• LECLERC Vincent (PH)
• LORIOT Marie Anne (PU-PH,HDR)
• MOUILLET-RICHARD Sophie (DR, HDR)
• MANCEAU Gilles (PU-PH, HDR)
• MARIANI Antoine (PHU)
• MEDIONI Jacques (MCU-PH)
• NARJOZ Céline (PH)
• PALLET Nicolas (PU-PH,HDR)
• PILATI Camilla (MCU)
• POINDESSOUS Virginie (IR)
• TALY Valérie (DR,HDR)
• TAIEB Julien (PU-PH, HDR)
• ZAANAN Aziz (PUPH, HDR)

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5 publications récentes et significatives de l’équipe de recherche

Lailler C, Didelot A, Garinet S, Berthou H, Sroussi M, de Reyniès A, Dedhar S, Martin-Lannerée S, Fabre E, Le Pimpec-Barthes F, Perrier A, Poindessous V, Mansuet-Lupo A, Djouadi F, Launay JM, Laurent-Puig P, Blons H, Mouillet-Richard S. PrPC controls epithelial-to-mesenchymal transition in EGFR-mutated NSCLC: implications for TKI resistance and patient follow-up. Oncogene. 2024 Sep;43(37):2781-2794. doi: 10.1038/s41388-024-03130-0. PMID: 39147880

Poindessous V, Sampaio JL, Bouidghaghen L, Nemazanyy I, Pallet A, Naesens M, Vaulet T, Anglicheau D, Pallet N. Interferon gamma induced-ACSL5 shapes the lipidome of kidney tubular cells. iScience. 2025 May 23;28(6):112742. doi: 10.1016/j.isci.2025.112742. PMID: 40546938

Pilati C, Soulabaille A, Gallois C, Blons H, Cayre A, Sroussi M, Le Corre D, Mouillet-Richard S, Mulot C, Le Malicot K, De Reynies A, Bachet JB, Borg C, Di Fiore F, Guimbaud R, Bennouna J, André T, Taieb J, Penault-Llorca F, Laurent-Puig P. ERBB2 Comprehensive Profiling and Prognostication in Stage III Colon Cancer: Findings From PETACC8 and IDEA-France Cohorts. Gastroenterology. 2025 Apr;168(4):714-724.e4. doi: 10.1053/j.gastro.2024.10.046. PMID: 39612956

Gallois C, Sroussi M, André T, Mouillet-Richard S, Agueeff N, Mulot C, Vernerey D, Louvet C, Bachet JB, Dourthe LM, Mazard T, Jary M, Coutzac C, Lecaille C, Tabernero J, Van Laethem JL, Lepage C, Emile JF, de Reyniès A, Taieb J, Laurent-Puig P. Prognostic Models From Transcriptomic Signatures of the Tumor Microenvironment and Cell Cycle in Stage III Colon Cancer From PETACC-8 and IDEA-France Trials. J Clin Oncol. 2025 May 20;43(15):1765-1776. doi: 10.1200/JCO.23.02262. PMID: 39889251

Beinse G, Taly V, Leary A, Baures A, Ray-Coquard I, You B, Rodrigues M, Gladieff L, Abadie-Lacourtoisie S, Bengrine-Lefevre L, Brachet PE, Lebreton C, Meynard G, Fournel P, Frenel JS, Selle F, Largillier R, Foa C, Cornila C, Kaczmarek E, Hardy-Bessard AC, D’Hondt V, Cojean Zelek I, Roche S, Duliege D, Mouret-Reynier MA, Bouchaert P, Laurent-Puig P, Joly F, Alexandre J. Circulating tumor DNA for prognostication and monitoring in patients with metastatic endometrial carcinoma treated with olaparib: validation in the GINECO-UTOLA trial. Clin Cancer Res. 2026 Jan 15. doi: 10.1158/1078-0432.CCR-25-2959. PMID: 41537701