Unité de recherche : Institut Pasteur
Institut Pasteur
PF cristallographie/ PFX
25 rue de Docteur Roux
75015 Paris
Spécialité : Biochimie , Biologie cellulaire ,Biologie moléculaire, Biologie structurale , Interface chimie-biologie , Microbiologie
Directeur de l’unité de rattachement : Paola ARIMONDO
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Responsable de l’équipe de recherche
HAOUZ Ahmed
Courriel : ahmed.haouz@pasteur.fr
Tél : 01 40 61 39 30
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Composition de l’équipe de recherche
- HAOUZ Ahmed (IR, HDR)
- MECHALLY Ariel (IR)
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5 publications récentes de l’équipe de recherche
Dejoux A, et al.,Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models. Sci Transl Med. 2024 Sep 11;16(764):eado4463. Epub 2024 Sep 11. PMID: 39259810.
Fernández I, Saunders N, Duquerroy S, Bolland WH, Arbabian A, Baquero E, Blanc C, Lafaye P, Haouz A, Buchrieser J, Schwartz O, Rey FA. Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus. Cell. 2024 Aug 8;187(16):4246-4260.e16. doi: 10.1016/j.cell.2024.06.007. Epub 2024 Jul 3. PMID: 38964326.
Legru A, et al., Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1. Eur J Med Chem. 2024 Apr 5;269:116308. Epub 2024 Mar 11. PMID: 38503166.
Le Coadou L, Berthelet J, Mechaly AE, Michail C, Bui LC, Dairou J, Haouz A, Dupret JM, Rodrigues Lima F. Structural and enzymatic evidence for the methylation of the ACK1 tyrosine kinase by the histone lysine methyltransferase SETD2. Biochem Biophys Res Commun. 2024 Feb 5;695:149400. Epub 2023 Dec 21. PMID: 38160530.
Weiß M, Giacomelli G, Assaya MB, Grundt F, Haouz A, Peng F, Petrella S, Wehenkel AM, Bramkamp M. The MksG nuclease is the executing part of the bacterial plasmid defense system MksBEFG. Nucleic Acids Res. 2023 Apr 24;51(7):3288-3306. doi: 10.1093/nar/gkad130. PMID: 36881760; PMCID: PMC10123090.