Unité de recherche : UMR1124
SysTox
Unité HealthFex UMR1124
45 rue des Saints Pères
75006 Paris
Spécialité : Biochimie, Biologie cellulaire , Biologie moléculaire, Biologie structurale, Interface chimie-biologie, Modélisation moléculaire, Toxicologie,
Directeur de l’unité de rattachement : Xavier COUMOUL
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Responsable de l’équipe de recherche
AUDOUZE Karine
Courriel: karine.audouze@u-paris.fr
Tél : 01 76 53 10 54
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Composition de l’équipe de recherche :
- AUDOUZE Karine (PR, HDR)
- MUNIER-LEHMANN Hélène (CR, HDR)
- MARGARITTE-JEANNIN (IR)
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5 publications récentes de l’équipe de recherche :
Comprehensive computational analysis via Adverse Outcome Pathways and Aggregate Exposure Pathways in exploring synergistic effects from radon and tobacco smoke on lung cancer Jaylet T, Chauhan V, Mezquita L, Boroumand N, Laurent O, Elihn K, Lundholm L, Armant O, Audouze K. Volume 13 – 2025. https://doi.org/10.3389/fpubh.2025.1571290
AOP-helpFinder 3.0: from text mining to network visualization of key event relationships, and knowledge integration from multiple sources Jaylet T, Jornod F, Capdet Q, Armant O, Audouze KBioinformatics. 2025 Jun 28:btaf381. doi: 10.1093/bioinformatics/btaf381.
The Cost Outcome Pathway framework: Integrating socio-economic impacts to Adverse Outcome Pathways for supporting policy makers Thibaut Coustillet, Angela Bearth, Xavier Coumoul, Anne-Sophie Villégier, Michèle Bisson, Ellen Fritsche, Jean-Marc Brignon, Florence Zeman, Karine Audouze. Toxicology. 2025; 517:154225.
https://doi.org/10.1016/j.tox.2025.154225
Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps. Jaylet T, Coustillet T, Smith NM, Viviani B, Lindeman B, Vergauwen L, Myhre O, Yarar N, Gostner JM, Monfort-Lanzas P, Jornod F, Holbech H, Coumoul X, Sarigiannis DA, Antczak P, Bal-Price A, Fritsche E, Kuchovska E, Stratidakis AK, Barouki R, Kim MJ, Taboureau O, Wojewodzic MW, Knapen D, Audouze K. Front Toxicol. 2024 Mar
8;6:1285768. doi: 10.3389/ftox.2024.1285768.
Exploring the multi-protein assembly of the enzymes of the de novo purine nucleotide biosynthetic pathway from Pseudomonas aeruginosa. Nour Ayoub, Nicolas Pietrancosta, Quentin Giai Gianetto, Gouzel Karimova, Antoine Gedeon, Hélène Munier-Lehmann. International Journal of Biological Macromolecules, 2025,
doi.org/10.1016/j.ijbiomac.2025.149706.